Risk factors and strategies for relapse prevention among individuals living with serious mental illness in South Africa: Qualitative inquiry from patients’ and caregivers’ perspectives

dc.contributor.authorProtas,Joyce
dc.date.accessioned2026-08-05T11:55:01Z
dc.date.available2026-08-05T11:55:01Z
dc.date.issued2024-08-22
dc.description.abstractIntroduction Relapse among individuals with serious mental illnesses in resource-limited contexts, including South Africa, is a significant concern. To date, the risks for relapse among this population is well documented, but little is known about prevention strategies to reduce its occurrence in these resource-limited settings. Therefore, this qualitative study explores the risk factors and strategies for relapse prevention from the patients’ and caregivers’ perspectives. Methods We conducted audio-recorded face-to-face in-depth interviews to capture the lived experience of relapse of inpatient study participants with serious mental illness (N = 24) at a public specialized psychiatry hospital in South Africa and their caregivers (N = 6). We conducted an inductive thematic analysis with two pre-specified themes (risk factors for relapse and strategies for prevention), with the codes devised from the data. Results Six sub-themes were identified from the analysis within the two pre-specified themes(Risk factors and strategies for relapse prevention): personal-related, family-related, and health system-related risk factors and strategies for preventing relapse, respectively. To highlight some essential findings, the importance of motivation for drug adherence, family involvement, and availability of anti-psychotic drugs in public health care were noted. More importantly, this study identified important cultural complexities where traditional healers play a significant role in some cultural understanding and treatment of mental illness, affecting medication adherence. Conclusion This study calls for people-centered mental health care delivery in a public health system that listens to the voice of concern, including cultural challenges, and implements meaningful support that matters most to the patient and their family/caregivers.
dc.identifier.citationMlay JP, Naidu T, Ramlall S, Mhlungu SS, Zondi M, Lessells R, et al. (2024) Risk factors and strategies for relapse prevention among individuals living with serious mental illness in South Africa: Qualitative inquiry from patients’ and caregivers’ perspectives. PLoS ONE 19(8): e0309238. https:// doi.org/10.1371/journal.pone.0309238
dc.identifier.issnhttps:// doi.org/10.1371/journal.pone.0309238
dc.identifier.urihttp://kuir.ku.ac.tz:4000/handle/123456789/1584
dc.language.isoen
dc.publisherPlos One
dc.subjectRelapse prevention
dc.subjectMental illness
dc.subjectSouth Africa
dc.titleRisk factors and strategies for relapse prevention among individuals living with serious mental illness in South Africa: Qualitative inquiry from patients’ and caregivers’ perspectives
dc.typeArticle

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