The association of 18 F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction
| dc.contributor.author | Mafuru, Magesa | |
| dc.date.accessioned | 2022-01-26T10:43:17Z | |
| dc.date.available | 2022-01-26T10:43:17Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Objective: The purpose of this study is to evaluate the association between PET/CT CFR and biomarkers combined in confirming the diagnosis of coronary microvascular dysfunction. Results: A total of 28 patients (21 males and 7 females) were included in this descriptive observational study (both qualitative and quantitative). The mean patient age was 55.50 ± 10.21 years (range 27–70 years) and the median was 56.5 years (range 49–63 years). All patients underwent Echo, CAG and PET/CT scan. Chest tightness was the most common symptom in our study. Most patients had normal blood pressure (n = 18, 64.3%) while only (n = 10, 37.5%) had hypertension, and (n = 1, 3.6%) had diabetes mellitus. The mean HDL in CMVD (n = 25) and non-CMVD (n = 3) were 1.30 ± 0.39 and 1.08 ± 0.95, respectively, indicating that the difference between the groups was statistically significant (p = 0.04). Similarly, the mean HBA1c- (glycated haemoglobin) in CMVD (n = 25) and non-CMVD (n = 3) were 5.6 ± 0.53 and 5.0 ± 0.26, respectively, with (p = 0.03). Our findings managed to show the association between biomarkers and PET/CT CFR in confirming the diagnosis of coronary microvascular dysfunction. Keywords: Coronary microvascular dysfunction (CMVD), Brain natriuretic peptide (BNP), Red cell distribution (RDW), Coronary flow reserve (CFR) | en_US |
| dc.identifier.citation | Mayala, H.A., Bakari, K.H., Mkangala, A., Magesa, M., Mghanga, F.P. and ZhaoHui, W., 2018. The association of 18 F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction. BMC research notes, 11(1), pp.1-6. | en_US |
| dc.identifier.other | doi.org/10.1186/s13104-018-3892-6 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/876 | |
| dc.language.iso | en | en_US |
| dc.publisher | BMC research notes | en_US |
| dc.subject | Coronary microvascular dysfunction (CMVD | en_US |
| dc.subject | Brain natriuretic peptide (BNP) | en_US |
| dc.subject | Red cell distribution (RDW) | en_US |
| dc.title | The association of 18 F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction | en_US |
| dc.type | Article | en_US |