The association of 18 F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction
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Date
2018
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BMC research notes
Abstract
Objective:
The purpose of this study is to evaluate the association between PET/CT CFR and biomarkers combined in confirming the diagnosis of coronary microvascular dysfunction.
Results:
A total of 28 patients (21 males and 7 females) were included in this descriptive observational study (both qualitative and quantitative). The mean patient age was 55.50 ± 10.21 years (range 27–70 years) and the median was 56.5 years (range 49–63 years). All patients underwent Echo, CAG and PET/CT scan. Chest tightness was the most common symptom in our study. Most patients had normal blood pressure (n = 18, 64.3%) while only (n = 10, 37.5%) had hypertension, and (n = 1, 3.6%) had diabetes mellitus. The mean HDL in CMVD (n = 25) and non-CMVD (n = 3) were 1.30 ± 0.39 and 1.08 ± 0.95, respectively, indicating that the difference between the groups was statistically significant (p = 0.04). Similarly, the mean HBA1c- (glycated haemoglobin) in CMVD (n = 25) and non-CMVD (n = 3) were 5.6 ± 0.53 and 5.0 ± 0.26, respectively, with (p = 0.03). Our findings managed to show the association between biomarkers and PET/CT CFR in confirming the diagnosis of coronary microvascular dysfunction.
Keywords: Coronary microvascular dysfunction (CMVD), Brain natriuretic peptide (BNP), Red cell distribution (RDW),
Coronary flow reserve (CFR)
Description
Keywords
Coronary microvascular dysfunction (CMVD, Brain natriuretic peptide (BNP), Red cell distribution (RDW)
Citation
Mayala, H.A., Bakari, K.H., Mkangala, A., Magesa, M., Mghanga, F.P. and ZhaoHui, W., 2018. The association of 18 F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction. BMC research notes, 11(1), pp.1-6.