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Item Awareness of colorectal cancer screening and its associated risk factors among adults attending outpatient clinics in regional referral hospitals in Dar es Salaam.(ISAR Journal of Medical and Pharmaceutical Sciences, 2024-11-28) Mziray, Amir N.; Mbembati, Naboth A.; Swai, Samuel P.; Wandwi, Wambura B.; Mkiramweni, Jerome P.; Kategile, Albert M.; Muganyizi, Daniel J.; Gangji, Raidah R.Background: Colorectal cancer screening aims to detect early signs of colorectal cancer before symptoms develop, increasing the chances of successful treatment and survival. Screening methods include colonoscopy, and stool-based tests like fecal occult blood tests (FOBT) or fecal immunochemical tests (FIT), which detect blood in the stool. Screening guidelines vary by country, but it is generally recommended to start regular screenings around age 40 for the average-risk individuals. Objective: To assess colorectal cancer (CRC) awareness, risk factors and screening utilizing FOBT and colonoscopy among participants in regional referral hospitals in Dar es Salaam. Methodology: A total of 150 participants were recruited for the study. FOBT was done to all participants, with positive cases undergoing further diagnostic interventions, including stool analysis, H. pylori antigen testing, and endoscopic interventions. Results: Of the 150 participants, 73.3% tested negative and 26.67% tested positive for FOBT. Further investigations revealed hookworm ova 12.5% (n=5/40) and H. pylori infection 22.5% (n=9/40) among FOBT positive cases. Conclusion: CRC screening using FOBT demonstrated significant number of positive cases, highlighting the need for improved awareness and education about CRC and its risk factors