Browsing by Author "Fedy Israel"

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    Helicobacter pylori infection and anaemia among pregnant women attending antenatal care at Mwananyamala regional referral hospital Dar es Salaam, Tanzania
    (Kairuki University, 2024) Fedy Israel
    Background: Helicobacter pylori (H. pylori) is a gram-negative bacterium commonly associated with gastrointestinal disorders. Its impact on anemia, particularly in pregnant women, is an area of growing interest, as pregnancy introduces additional nutritional and physiological stresses that can exacerbate anemia. Objective: To investigate the effects of H. pylori infection on anemia in pregnant women attending antenatal care at Mwananyamala Regional Referral Hospital between May and June 2024. Methods: This study involved a cross-sectional hospital-based analysis of 300 pregnant women attending antenatal clinics. Participants were screened for H. pylori infection using stool antigen tests. FBP was measured to hemoglobin level, and additional tests were a blood sample for malaria parasites and a stool sample for HP infection and intestinal worms. Also, MUAC was done to assess the malnutrition status of the participants. Clinical data, including demographic and obstetric history, were also collected. SPSS version 20 was used for data analysis; bivariate multivariable logistic regression used for confound factors analysis and Chi square were used for exploration of the association of HP infection on anemia in pregnant women. Results: There were effects of H. pylori infection on increased prevalence of anemia among pregnant women who had H. pylori infection, H.P Infection were 2.4 times (AOR = 2.40, 95% CI = 1.354-3.674) more likely to be anemic than the H. pylori-negative ones. Independent of confounding factors associated with increased anemia were education levels (AOR = 3.24, 95% CI = 1.58-6.63), occupation (AOR = 1.90, 95% CI = 0.99-3.72), third-trimester pregnancy (AOR = 1.97, 95% CI = 1.01-2.2), and history of hyperemesis gravidurum (AOR = 6.42, 95% CI = 2.97-13.91). Conclusion: H. pylori infection has effects on anemia in pregnant women. The infection appears to exacerbate the risk of anemia, likely through mechanisms related to impaired iron absorption and increased gastrointestinal inflammation. These findings highlight the importance of screening and managing H. pylori infection as part of prenatal care to improve maternal and fetal health outcomes.